Table 1. Identification of DNA repair genes whose expression is associated with patients' prognostic value using HM cohort.

Out of the 84 DNA repair genes, 22 had prognostic value for both event-free survival (EFS) and overall survival (OS) using R MaxStat function. Genes are ranked according to the FDR of log-rank test for overall survival. FDR: false discovery rate; HR: hazard ratio.

				Overall Survival			Event Free Survival
Probe set	Gene Name	DNA repair pathway	Prognostic value	Maxstat cut-point	FDR	HR	Maxstat cut-point	FDR	HR
218979_at	RMI1	FA	BAD	1356	1.E-04	5	1353	6.E-04	3.0
201202_at	PCNA	NER	BAD	3703	1.E-04	4.5	2446	9.E-04	2.2
222777_s_at	WHSC1/MMSET	NHEJ	BAD	1506	3.E-04	3.7	918	3.E-05	2.8
204603_at	EXO1	HR/MMR	BAD	295	8.E-04	3.9	48	4.E-02	1.8
213007_at	FANCI	FA	BAD	648	9.E-04	3.5	179	1.E-02	2.4
226503_at	RIF1	NHEJ	BAD	1273	2.E-03	3.2	1273	2.E-03	2.3
205733_at	BLM	HR	BAD	1450	4.E-03	2.9	1495	2.E-02	1.8
209421_at	MSH2	MMR	BAD	608	3.E-02	2.7	352	3.E-02	1.6
209507_at	RPA3	HR/NER	BAD	3902	3.E-02	3.2	3836	5.E-04	3.1
204123_at	LIG3	NER/BER	BAD	502	3.E-02	2.6	435	4.E-03	2.0
212836_at	POLD3	NER	BAD	262	3.E-02	6.3	247	2.E-02	2.1
205024_s_at	RAD51	HR	BAD	641	3.E-02	2.8	514	5.E-02	1.7
208642_s_at	XRCC5/ KU80	NHEJ	BAD	7702	4.E-02	2.9	7626	2.E-03	2.5
235215_at	ERCC4	NER	BAD	1103	4.E-02	2.5	873	1.E-03	2.2
203805_s_at	FANCA	FA	BAD	271	4.E-02	2.2	140	1.E-02	2.4
203422_at	POLD1	NER	BAD	762	5.E-02	2.4	714	1.E-02	2.0
205395_s_at	MRE11A	HR	BAD	544	5.E-02	2.1	542	1.E-02	1.8
203720_s_at	ERCC1	NER	GOOD	1885	4.E-02	0.4	3184	2.E-02	0.4
218961_s_at	PNKP	NHEJ	GOOD	1473	4.E-02	0.4	1346	2.E-03	0.5
221049_s_at	POLL	NHEJ	GOOD	101	5.E-02	0.3	42	5.E-03	0.5
202414_at	ERCC5	NER	GOOD	645	5.E-02	0.5	695	5.E-03	0.5
212672_at	ATM	HR	GOOD	1570	5.E-02	0.5	1575	3.E-02	0.6