Table 5. Link of DRscore with patients' genetic abnormalities Interphase-FISH-analysis was performed on CD138-purified plasma cells of 153 to 169 patients of the HM series, depending on the gene abnormality.
Patients were separated in two groups according to DRscore (low-risk and high-risk groups). Data are the percentages of patients within these 2 groups with the biological parameters. When the percentages were different with a chisquare test (P ≤.05), data are shown in bold.
| DRscore ≤ −7.62 | DRscore > −7.62 | |
|---|---|---|
| t(11;14)+(n = 27) | 17% | 15% |
| t(11;14)-(n = 140) | 83% | 85% |
| t(4;14)+(n = 28) | 13% | 28% |
| t(4;14)-(n = 137) | 87% | 72% |
| 1q21+(n = 62) | 33% | 59% |
| 1q21-(n = 91) | 67% | 41% |
| del13+(n = 91) | 45% | 77% |
| del13-(n = 78) | 55% | 23% |
| del17+(n = 27) | 14% | 24% |
| del17-(n = 132) | 85% | 76% |