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. 2014 Apr 18;5(9):2778–2791. doi: 10.18632/oncotarget.1916

Figure 5. A549 (A-B) and HeLa (C-D) sensitivity to gamma irradiation (4 Gy) before (A and C) and after (B and D) IDO induction.

Figure 5

Results were obtained from independent measurements of proliferation of 3 A549 or HeLa clonal populations harboring control scrambled shRNA and 3 harboring anti-IDO shRNA. Bars represent the means of 3 independent measurements (n=3 for each measurement) ± SEM (*p≤0.05). IDO in A549 (E) and HeLa (F) clones decreases the effectiveness of gamma irradiation. Results were obtained from independent measures of proliferation of 3 A549 or HeLa clonal populations harboring control scrambled shRNA and 3 harboring anti-IDO shRNA. Bars represent the means of those 3 independent measurements (n=3 for each measurement) ± SEM. *Different from cells treated identically but without IFN gamma induction (p≤0.05, Student's t-test).