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. 2014 Apr 24;5(9):2807–2819. doi: 10.18632/oncotarget.1921

Table 2. Combination index of the HCT 116 isogenic cell lines, namely p21 +/+ and p21 −/- were studied.

Synergy was observed in the former, while antagonism was seen in the latter.

Cell Line ED50 ED75
1 HCT116 p21 +/+ 0.56315 0.64849
2 HCT116 p21 −/− 2.46 × 103 6.19 × 104