Table 3.
Development of ear/palate itching during the study (d1 to d14 or V1 to V2) as assessed by patients and investigators. The total number of patients (% given in brackets) where symptoms were reduced, unchanged, or deteriorated is shown.
| Ear/palate itching | Patients' assessment | Total | Physicians' assessment | Total | ||
|---|---|---|---|---|---|---|
| Group 1 | Group 2 | Group 1 | Group 2 | |||
| Reduced | 4 (17.4%) | 12 (48.0%) | 16 (33.3%) | 12 (48.0%) | 14 (56.0%) | 26 (52.0%) |
| Unchanged | 14 (60.9%) | 9 (36.0%) | 23 (47.9%) | 12 (48.0%) | 8 (32.0%) | 20 (40.0%) |
| Deteriorated | 5 (21.7%) | 4 (16.0%) | 9 (18.8%) | 1 (4.0%) | 3 (12.0%) | 4 (8.0%) |
| Total | 23 (100.0%) | 25 (100.0%) | 48 (100.0%) | 25 (100.0%) | 25 (100.0%) | 50 (100.0%) |
| Fisher's exact test | P = 0.088 | P = 0.357 | ||||