Table 1.
Biochemical tests of haloperidol- (HA-) intoxicated rabbits receiving various doses of intravenous lipid emulsion (ILE) or normal saline, 24 hours after starting HA or AWD infusion. Data are reported in means ± standard error.
| Lab test (unite) |
ADW + normal saline 18 mL/kg | ADW + 18 mL/Kg ILE |
HA + normal saline 18 mL/kg | HA + ILE 6 mL/kg | HA + ILE 12 mL/kg | HA + ILE 18 mL/kg |
|---|---|---|---|---|---|---|
| Blood urea nitrogen (mg/dL) | 16 ± 1.68 | 18.0 ± 2.55 | 29.0 ± 8.45** | 18.2 ± 3.11 | 23.4 ± 12.66 | 40.3 ± 18.52* |
| Serum creatinine (mg/dL) |
1.16 ± 0.007 | 1.1 ± 0.063 | 1.82 ± 0.57 | 1.08 ± 0.08 | 1.14 ± 0.144 | 1.5 ± 0.141 |
| Alanine transaminase (IU/L) |
61.0 ± 5.1 | 62.5 ± 11.6 | 54.0 ± 13.4 | 57.3 ± 8.8 | 86.5 ± 4.6* | 83.0 ± 8.5* |
| Aspartate transaminase (IU/L) |
39.3 ± 6.3 | 67.8 ± 19.8 | 130.8 ± 63.5 | 42.5 ± 4.6 | 82.3 ± 29.8 | 314.0 ± 64.6* |
| Alkaline Phosphatase (IU/L) |
243.5 ± 57.56 | 153.5 ± 38.86 | 379.5 ± 49.46 | 293.75 ± 23.83 | 342.2 ± 59.63 | 388.5 ± 48.5 |
| Amylase (U/L) | 274.4 ± 13.12 | 226.2 ± 29.05 | 234.6 ± 24.44 | 214 ± 19.20 | 269 ± 26.21 | 443.0 ± 120.9 |
| Lipase (U/L) | 215.5 ± 25.83 | 128.75 ± 33.62 | 147.0 ± 27.66 | 162.25 ± 42.13 | 226.5 ± 43.51 | 495.0 ± 228.5 |
*P < 0.05,**P < 0.01, ADW: aseptic distilled water.