. 2014 May 29;2014:327606. doi: 10.1155/2014/327606

Table 2.

Results of aspirin induced ulcerogenesis in pyloric ligation model.

Parameters	Various groups
	Negative control	Ranitidine	Aqueous extract of Channa striata
	Negative control	50 mg/kg	30% w/v	40% w/v	50% w/v
Volume of gastric juice (mL)	5.43 ± 0.22	4.36 ± 0.17**	5.26 ± 0.16^ns	4.53 ± 0.16*	4.23 ± 0.32**
pH	3.83 ± 0.108	4.95 ± 0.16**	3.33 ± 0.33^ns	3.68 ± 0.18^ns	3.65 ± 0.084^ns
Free acidity	51.00 ± 2.85	40.00 ± 2.47*	45.00 ± 2.72^ns	44.00 ± 1.59^ns	39.33 ± 2.97*
Total acidity	93.17 ± 1.86	85.50 ± 1.40**	90.50 ± 1.72^ns	90.17 ± 1.74^ns	86.67 ± 1.20*
Ulcer index	5.91 ± 0.45	2.75 ± 0.38***	4.00 ± 0.36**	3.75 ± 0.38**	3.08 ± 0.35***
Percentage of inhibition	—	53.46%	32.31%	36.54%	47.88%
Catalase (units/mg of tissue)	0.011 ± 0.011	0.059 ± 0.0032**	0.041 ± 0.0079^ns	0.066 ± 0.0064**	0.072 ± 0.012***
Superoxide dismutase (units/mg of tissue)	0.015 ± 0.010	0.071 ± 0.0094**	0.027 ± 0.0050^ns	0.047 ± 0.012^ns	0.055 ± 0.013*
Malondialdehyde (moles/mg of tissue)	0.190 ± 0.0012	0.089 ± 0.0013^∗∗∗	0.088 ± 0.0034^∗∗∗	0.085 ± 0.0078^∗∗∗	0.072 ± 0.013***

Note: sample size (n) = 6 rats per group. Data is expressed as mean ± standard error of mean and standard deviation in parenthesis. *P < 0.05, **P < 0.01, ***P < 0.001 and ns nonsignificant versus negative control (on statistical analysis with ANOVA, followed by Dunnett's multiple comparison post hoc test).