Table 2.
Echocardiographic parameters—overview of ventricular remodeling effects.
| Sham | Model | FS | SNT-LD | SNT-HD | Remodeling effects (versus model) |
|
|---|---|---|---|---|---|---|
| LVDd (mm) | 3.29 ± 0.81 | 6.24 ± 0.72 | 4.45 ± 1.28** | 5.37 ± 1.78 | 4.87 ± 1.47 | ↓ |
| LVDs (mm) | 0.91 ± 0.20 | 6.44 ± 1.59** | 3.81 ± 1.21∗∗▲▲ | 4.95 ± 1.95** | 3.74 ± 1.47∗∗▲▲ | ↓ |
| EF (%) | 93.32 ± 2.94 | 55.48 ± 12.89** | 78.03 ± 10.70∗▲▲ | 69.69 ± 13.91∗▲ | 77.83 ± 12.32∗∗▲▲ | ↑ |
| IS (mm2) | 38.04 ± 8.35 | 23.91 ± 7.99▲▲ | 31.25 ± 10.68 | 27.81 ± 4.91▲ | ↓ | |
| HW/BW (mg/g) | 0.31 ± 0.01 | 0.37 ± 0.07 | 0.36 ± 0.08 | 0.35 ± 0.08 | 0.36 ± 0.07 | ↓ |
| LVAC/HCA (%) | 10.82 ± 3.01 | 22.30 ± 3.92** | 15.17 ± 6.54▲▲ | 18.48 ± 3.96* | 15.25 ± 2.78▲ | ↓ |
*P < 0.05, **P < 0.01 versus sham group; ▲ P < 0.05, ▲▲ P < 0.01 versus model group.