Table 4.
Sham | Model | FS | SNT-LD | SNT-HD | Expression levels (versus model) |
|
---|---|---|---|---|---|---|
In serum | ||||||
Collagen I (μg/L) | 2.74 ± 0.40 | 4.11 ± 0.74** | 2.67 ± 0.42▲▲ | 2.43 ± 0.38▲▲ | 2.17 ± 0.21▲▲ | ↓ |
Collagen III (μg/L) | 1.61 ± 0.27 | 2.68 ± 0.43** | 2.00 ± 0.45▲▲ | 2.02 ± 0.47▲▲ | 1.96 ± 0.47▲▲ | ↓ |
TGF-β1 (ng/L) | 24.95 ± 4.31 | 23.91 ± 5.76 | 22.84 ± 5.07 | 23.75 ± 8.78 | 25.61 ± 7.98 | |
In myocardial tissue | ||||||
Collagen I (μg/g) | 0.94 ± 0.16 | 1.20 ± 0.15 | 0.86 ± 0.15▲ | 1.03 ± 0.10 | 0.89 ± 0.14▲ | ↓ |
Collagen III (μg/g) | 0.28 ± 0.10 | 0.45 ± 0.04* | 0.33 ± 0.04 | 0.36 ± 0.08 | 0.30 ± 0.04▲ | ↓ |
TGF-β1 (ng/g) | 5.99 ± 2.17 | 6.48 ± 1.79 | 5.91 ± 2.80 | 5.32 ± 0.49 | 4.08 ± 1.05 | ↓ |
*P < 0.05, **P < 0.01 versus sham group; ▲ P < 0.05, ▲▲ P < 0.01 versus model group.