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. 2014 May 25;2014:185716. doi: 10.1155/2014/185716

Table 2.

Antioxidants status in the tissue and blood of mice in each group.

Index GroupC Brain Liver Kidney Serum
MDA (nmol/mg prot or nmol/mL) Model 7.09 ± 1.27 4.31 ± 1.10 5.07 ± 0.71 7.07 ± 0.58
Control 5.47 ± 0.62a 2.23 ± 0.97a 3.89 ± 0.51a 5.21 ± 0.58a
VC 4.87 ± 0.94b 2.27 ± 0.36b 3.80 ± 0.68a 4.92 ± 0.22a
Low dose 5.53 ± 0.39a 3.21 ± 1.15 4.76 ± 0.77 5.11 ± 0.70a
Medium dose 4.77 ± 0.51b# 2.57 ± 0.48a 3.61 ± 0.80b 4.73 ± 0.20a
High dose 4.16 ± 0.50b## 2.03 ± 0.63b 2.87 ± 0.53bA# 5.44 ± 0.63a

SOD (U/mg prot or U/mL) Model 139.29 ± 17.74 281.25 ± 31.04 153.42 ± 5.21 96.64 ± 4.39
Control 211.64 ± 38.02b 368.10 ± 35.78b 195.91 ± 16.30b 121.70 ± 9.45a
VC 181.12 ± 29.52b 384.02 ± 27.66b 145.91 ± 16.87## 131.65 ± 13.05a
Low dose 158.62 ± 21.84a# 349.21 ± 34.90aA 171.10 ± 14.59aA# 96.41 ± 10.65A
Medium dose 167.80 ± 33.06a# 353.29 ± 22.14bA 184.68 ± 13.35bB 102.26 ± 5.46A#
High dose 175.24 ± 22.22b# 320.61 ± 35.27aB# 189.27 ± 14.75bB 115.62 ± 8.24a

GSH (mgGSH/g prot or mgGSH/L) Model 2.96 ± 0.70 1.10 ± 0.20 1.52 ± 0.25 6.81 ± 0.58
Control 5.59 ± 0.86b 1.72 ± 0.10b 2.53 ± 0.16b 12.56 ± 0.40b
VC 3.93 ± 0.45a## 1.59 ± 0.19a 2.29 ± 0.26b 7.68 ± 0.38##
Low dose 4.52 ± 0.86a# 1.30 ± 0.33# 1.63 ± 0.35B## 7.62 ± 0.34##
Medium dose 5.83 ± 0.66bB 1.56 ± 0.35b 1.99 ± 0.29b# 7.98 ± 0.21a##
High dose 7.09 ± 0.98bB# 2.32 ± 0.33bB## 2.52 ± 0.33b 9.17 ± 0.42bA##

GSH-Px (U/mg prot or U/mL) Model × 415.35 ± 47.62 114.84 ± 8.83 459.67 ± 27.24
Control 657.42 ± 53.53b 174.17 ± 11.01b 680.33 ± 21.51b
VC 511.67 ± 23.93b## 159.10 ± 16.63b 626.41 ± 16.88b#
Low dose 430.81 ± 42.50B## 151.54 ± 21.95b# 508.21 ± 20.52aB##
Medium dose 602.80 ± 67.82bB# 169.50 ± 16.33b 650.73 ± 14.10bA
High dose 493.69 ± 34.11b## 194.91 ± 20.63bB# 576.38 ± 14.50bA##

CAT (U/g prot or U/mL) Model × 295.67 ± 36.16 120.01 ± 13.85 5.42 ± 0.29
Control 340.24 ± 34.51a 166.53 ± 34.24b 9.71 ± 0.70b
VC 394.63 ± 62.56b 149.67 ± 29.17a 12.91 ± 1.19b
Low dose 317.88 ± 22.79A 148.28 ± 24.34a 8.61 ± 0.47bB
Medium dose 403.77 ± 41.93b# 233.29 ± 42.72bB# 9.67 ± 0.20bA
High dose 522.61 ± 31.60bB## 158.70 ± 24.30a 11.42 ± 0.27b#

T-AOC (U/mg prot or U/mL) Model 0.83 ± 0.21 1.23 ± 0.10 0.59 ± 0.06 4.56 ± 0.39
Control 1.41 ± 0.28b 1.66 ± 0.17b 1.00 ± 0.15b 6.52 ± 0.28b
VC 2.48 ± 0.23b## 1.36 ± 0.22# 0.46 ± 0.08## 6.78 ± 0.04b
Low dose 1.38 ± 0.22bB 1.34 ± 0.10# 1.18 ± 0.08bB# 5.38 ± 0.23aA#
Medium dose 1.53 ± 0.24bB 1.58 ± 0.16b 1.25 ± 0.11bB# 5.85 ± 0.26bA#
High dose 1.92 ± 0.15bB## 1.88 ± 0.16bB# 1.48 ± 0.13bB## 6.31 ± 0.30b

Values are the mean ± SD.

× means undetected.

a P < 0.05; b P < 0.01 compared with model group (all groups). A P < 0.05; B P < 0.01 compared with VC group (EAE groups). # P < 0.05; ## P < 0.01 compared with control group (VC and EAE groups). CVC group (100 mg/kg); low dose EAE group (100 mg/kg); medium dose EAE group (200 mg/kg); high dose EAE group (400 mg/kg).