Figure 2.

Survival and differentiation of BMSCs in the transected spinal cord at 8 w after transplantation. Although many CFDA-SE labeled BMSCs are surrounded by numerous OX42-positive macrophages at 2 w after transplantation (A), very few cells survive at 8 w at the lesioned epicenter (B). (C) Cells at a higher magnification (B). The BMSCs (D) surviving after transplantation retain fibronectin immunoreactivity (E, F), and a few (G) display faint NeuN-immunoreactivity (H, I). Scale bar, 200 μm (A, B), 100 μm (C), 20 μm (D-F) and 10 μm (G-I).