Fig. 2.
Multiple sequence alignment of Amblyomma americanum (Aam)AV422 amino acid sequence with homologs in other ticks (A) and non-tick arthropods (B). Amino acid sequences were aligned using the CustalWsequence alignment tool in MacVector DNA analysis software. Conserved amino acid residues are shaded gray. Stars (★) denotes conserved cysteine amino acid residues. Sequences are denoted by an abbreviation of their species name followed by their GenBank accession number. AamAV422, A. americanum (KC222016); Rhimic, Rhipicephalus microplus (CK189031); Rhapp, Rhipicephalus appendiculatus (CD782378); Amac, Amblyomma maculatum (AE033794, AE035804, AE036190); Avar, Amblyomma variegatum (DAA34157 and BM293119); Ixsc, Ixodes scapularis (Y66605, EEC1287, EEC13894, EEC18200, EEC18201, EEC18204, EEC18638, EEC18639 and EEC19641); Angamb, Anopheles gambiae (EAA00770); Meu, Mesobuthus eupeus (ABR21053); Hoju, Hottentotta judaica (ADY39539); Bter, Bombus terrestris (XP_003396818); Dyak, Drosophila yakuba (EDW92254).