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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Mol Cancer Res. 2014 Mar 11;12(6):912–923. doi: 10.1158/1541-7786.MCR-13-0620-T

Figure 2. Loss of Cdkn2ab increases proliferation, and tumor progression in mutant Kras lung tumors.

Figure 2

(A) Images of lung tumors stained with the indicated antibodies (100X). Antibody staining is shown in brown, nuclear fast red counter-stain is pink-red. Arrows show location of inlets. A – Adenoma, AC – Adenocarcinoma, T – tumor, N - normal tissue. (B) Histogram of the percentage of p-H3 positive cells lung tumors. (C) Sections of lung tumors stained as indicated (100X). Arrows indicate the location of inlets. (D) Histogram representing percentage of lung tumors with the indicated HMGA2 staining pattern (refer to methods for scoring scale). (E) Anatomic location and classification of HMGA2 positive tumors. Number of tumors is indicated.