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. Author manuscript; available in PMC: 2015 Jun 1.
Published in final edited form as: Mol Cancer Res. 2014 Mar 11;12(6):912–923. doi: 10.1158/1541-7786.MCR-13-0620-T

Figure 6. Reintroduction of p15INK4B in CDKN2AB deficient lung cancer cell lines causes in growth arrest and apoptosis.

Figure 6

(A) Cell cycle analysis of A549 and H460 cells after 72h of luciferase or p15INK4B expression. Both cell lines show an increase in the G1 phase of the cell cycle. A549 cells also showed an increase in Sub-G1 fraction suggesting a portion of cells undergoes apoptosis. (B) Western blot analysis of A549 and H460 cells transduced as indicated. L: luciferase.