Table 3.
Constituent area fractions and percentage of the wall for the media and adventitia for each of the three groups. Note that the elastin area fraction (φe) represents elastin and the other microfibrillar proteins that constitute the elastic fibers, the smooth muscle area fraction (φm) represents cell cytoplasm that is highly localized to the smooth muscle cells, and the collagen area fraction (φc) represents fibrillar collagen and associated glycoproteins. Each measurement has a sample size of n = 12, with values presented as means ± standard deviation. The superscript (*) denotes a statistically significant difference, compared to the untreated control group, at a value of p<0.05.
| Group | Elastin (φe) | Smooth Muscle (φm) | Collagen (φc) | % Media | % Adventitia |
|---|---|---|---|---|---|
| Untreated | 0.258 ± 0.020 | 0.205 ± 0.045 | 0.500 ± 0.106 | 37.71 ± 3.48 % | 62.29 ± 3.24 % |
| ANG-II without AAA | 0.242 ± 0.023 | 0.207 ±0.011 | 0.567 ± 0.053 | 42.82 ±3.08 % * | 57.18 ±3.08 % * |
| ANG-II with AAA | 0.286 ± 0.029 * | 0.209 ± 0.024 | 0.556 ± 0.086 | 44.18 ±2.56 % * | 55.82 ±2.56 % * |