Table 3. Changes in Pulmonary Function (PF) Following SBRT: The RTOG SBRT Pulmonary Toxicity Scale Percent (%) of Patients Experiencing Each Grade of PF Toxicity is Shown.
| PF Toxicity at Any Time During the 2-year Post-SBRT Follow-up | PF Toxicity at 6 Weeks Post-SBRT | PF Toxicity at 2 Years Post-SBRT | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pulmonary Function Test | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 0 | Grade 1 | Grade 2 | Grade 3 | Grade 0 | Grade 1 | Grade 2 | Grade 3 |
| (n=49) | (n=37) | (n=21) | ||||||||||
| FVC (L) | 42.9% | 40.8% | 16.3% | 0.0% | 73.0% | 24.3% | 2.7% | 0.0% | 71.4% | 14.3% | 14.3% | 0.0% |
| FVC (% Predicted) | 40.8% | 40.8% | 18.4% | 0.0% | 75.7% | 16.2% | 8.1% | 0.0% | 71.4% | 19.0% | 9.5% | 0.0% |
| (n=49) | (n=37) | (n=21) | ||||||||||
| FEV1 (L) | 38.8% | 36.7% | 18.4% | 6.1% | 81.1% | 13.5% | 2.7% | 2.7% | 47.6% | 38.1% | 14.3% | 0.0% |
| FEV1 (% Predicted) | 32.7% | 42.9% | 22.4% | 2.0% | 75.7% | 16.2% | 5.4% | 2.7% | 52.4% | 38.1% | 9.5% | 0.0% |
| (n=40) | (n=29) | (n=15) | ||||||||||
| DLCO (ml/min/mmHg)* | 35.1% | 18.9% | 45.9% | 0.0% | 75.9% | 13.8% | 10.3% | 0.0% | 46.7% | 26.7% | 26.7% | 0.0% |
| DLCO (% Predicted)* | 21.6% | 29.7% | 48.6% | 0.0% | 65.5% | 27.6% | 6.9% | 0.0% | 33.3% | 26.7% | 40.0% | 0.0% |
L = Liter; n = number of patients.