Table 4. Logistic Regression Models Any Pulmonary/Upper Respiratory Toxicity Baseline Pulmonary Function Tests.
Any Pulmonary Toxicity | Grade 3+ Pulmonary Toxicity | |||||
---|---|---|---|---|---|---|
Pulmonary Function Test | Events/Total | OR (95% CI) | p-value | Events/Total | OR (95% CI) | p-value |
FVC (Actual) | 31 / 51 | 1.74 (0.71, 4.24) | 0.2037 | 8 / 51 | 1.21 (0.42, 3.47) | 0.7317 |
FVC (% Predicted) | 31 / 51 | 1.01 (0.99, 1.04) | 0.2867 | 8 / 51 | 0.99 (0.96, 1.03) | 0.7450 |
FEV1 (Actual) | 31 / 51 | 2.52 (0.87, 7.33) | 0.0665 | 8 / 51 | 0.85 (0.25, 2.94) | 0.7958 |
FEV1 (% Predicted) | 31 / 51 | 1.01 (0.99, 1.03) | 0.1589 | 8 / 51 | 0.99 (0.97, 1.02) | 0.4973 |
FEV1/FVC (Actual) | 31 / 51 | NA - unstable | -- | 8 / 51 | NA - unstable | -- |
FEV1/FVC (% Pred.) | 31 / 51 | NA - unstable | -- | 8 / 51 | 0.34 (0.01, 8.21) | 0.5004 |
RV (Actual) | 26 / 39 | 0.74 (0.38, 1.45) | 0.3760 | 7 / 39 | 1.09 (0.49, 2.45) | 0.8284 |
RV (% Predicted) | 26 / 39 | 1.00 (0.99, 1.01) | 0.7236 | 7 / 39 | 0.99 (0.98, 1.01) | 0.4692 |
TLC (Actual) | 26 / 39 | 0.84 (0.51, 1.37) | 0.4791 | 7 / 39 | 1.10 (0.61, 1.99) | 0.7488 |
TLC (% Predicted) | 26 / 39 | 0.98 (0.94, 1.01) | 0.1944 | 7 / 39 | 0.97 (0.93, 1.02) | 0.2359 |
DLCO (Actual) | 26 / 42 | 1.03 (0.86, 1.23) | 0.7468 | 8 / 42 | 0.90 (0.71, 1.13) | 0.3504 |
DLCO (% Predicted) | 26 / 42 | 1.00 (0.98, 1.02) | 0.8829 | 8 / 42 | 0.97 (0.92, 1.01) | 0.0617 |
PaCO2 | 22 / 37 | 1.03 (0.92, 1.14) | 0.6364 | 9 / 37 | 1.01 (0.90, 1.13) | 0.9028 |
PaO2 | 22 / 37 | 1.00 (0.95, 1.05) | 0.9705 | 9 / 37 | 1.00 (0.95, 1.06) | 0.8601 |
SaO2 | 20 / 33 | 1.01 (0.86, 1.19) | 0.8765 | 9 / 33 | 1.02 (0.85, 1.22) | 0.8230 |
OR = odds ratio