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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Int J Radiat Oncol Biol Phys. 2014 Apr 1;88(5):1092–1099. doi: 10.1016/j.ijrobp.2013.12.050

Table 5. Normal Lung Dose Volume Distributions by Development of Pneumonitis.

Parameter All Patients (n = 45) Patients without Pneumonitis (n = 36) * Patients with Pneumonitis (n = 9) OR (95% CI) p-value
Whole Lung V20 (%) 4.8 ± 2.3 4.7 ± 2.3 5.2 ± 2.4 1.08 (0.80, 1.47) p = 0.62
Whole Lung V10 (%) 11.9 ± 5.1 12.0 ± 5.6 11.8 ± 3.3 0.99 (0.86, 1.15) p = 0.94
Whole Lung V5 (%) 19.0 ± 6.9 18.8 ± 7.2 19.8 ± 5.7 1.02 (0.92, 1.13) p = 0.71
Mean Dose to Whole Lung (Gy) 4.0 ± 1.5 3.9 ± 1.6 4.1 ± 1.2 1.10 (0.69, 1.76) p = 0.69

Values are expressed as mean ± SD, n = number of patients

OR = odds ratio, CI = confidence interval

V20 = volume receiving 20 Gy, V10 = volume receiving 10 Gy, V5 = volume receiving 5 Gy

*

Toxicity was graded using CTCAE v3.0. Nine patients had grade 1-3 pneumonitis. No patient had grade 4, or grade 5 pneumonitis