Table 5. Normal Lung Dose Volume Distributions by Development of Pneumonitis.
Parameter | All Patients (n = 45) | Patients without Pneumonitis (n = 36) | * Patients with Pneumonitis (n = 9) | OR (95% CI) | p-value |
---|---|---|---|---|---|
Whole Lung V20 (%) | 4.8 ± 2.3 | 4.7 ± 2.3 | 5.2 ± 2.4 | 1.08 (0.80, 1.47) | p = 0.62 |
Whole Lung V10 (%) | 11.9 ± 5.1 | 12.0 ± 5.6 | 11.8 ± 3.3 | 0.99 (0.86, 1.15) | p = 0.94 |
Whole Lung V5 (%) | 19.0 ± 6.9 | 18.8 ± 7.2 | 19.8 ± 5.7 | 1.02 (0.92, 1.13) | p = 0.71 |
Mean Dose to Whole Lung (Gy) | 4.0 ± 1.5 | 3.9 ± 1.6 | 4.1 ± 1.2 | 1.10 (0.69, 1.76) | p = 0.69 |
Values are expressed as mean ± SD, n = number of patients
OR = odds ratio, CI = confidence interval
V20 = volume receiving 20 Gy, V10 = volume receiving 10 Gy, V5 = volume receiving 5 Gy
Toxicity was graded using CTCAE v3.0. Nine patients had grade 1-3 pneumonitis. No patient had grade 4, or grade 5 pneumonitis