Table 2.
Summary of the number of differentially expressed genes between the studied groups.
Comparison | P < 0.01 adjusted for multiple comparison P < 0.01 | P < 0.01; fold change >1.5 | |
---|---|---|---|
5th DOL | Genes presented a positive monotone trend (expression in extremely preterm is lower than that in very preterm; expression in very preterm is lower than that in moderately preterm) | 56 | |
Genes presented a negative monotone trend | 82 | ||
| |||
28th DOL | Genes presented a positive monotone trend | 253 | |
Genes presented a negative monotone trend | 55 | ||
| |||
5th DOL versus 28th DOL (paired t-test) | Genes whose expressions were significantly higher on the 28th DOL compared to those on the 5th DOL | 1522 | 150 |
Genes whose expressions were significantly lower on the 28th DOL compared to those on the 5th DOL | 2909 | 337 | |
| |||
Extremely preterm infants measurement on the 28th DOL versus very preterm infants measurements on the 5th DOL | Genes whose expressions were significantly higher in the group of extremely preterm infants compared to those in the group of very preterm infants | 176 | 29 |
Genes whose expressions were significantly lower in the group of extremely preterm infants compared to those in the group of very preterm infants | 186 | 27 |