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. 2014 May 27;2014:263786. doi: 10.1155/2014/263786

Figure 5.

Figure 5

Niacin decreased the secretion of TNF-α and IL-6 and inhibited NF-κB and notch1 expression in oxLDL-stimulated THP-1 macrophages. (a) and (b) show the relative levels of TNF-α and IL-6 secretion in the medium of THP-1 macrophages. The concentrations of IL-6 and TNF-α were determined by ELISA kit. (c) and (d) show the representative images of NF-κB p65 and notch1 protein expression in THP-1 macrophages by western blot. (e) and (f) show the IOD ratios of NF-κB p65 and notch1 expression, respectively. Data are presented as mean ± SD. ## P < 0.01 versus blank group; *P < 0.05; **P < 0.01 versus oxLDL-treated group without niacin.