Table 1.

Effect of niacin and simvastatin on plasma inflammatory markers (CRP, IL-6, and TNF-α) of guinea pig fed high fat diet.

Group	CRP (ng/L)	IL-6 (ng/L)	TNF-α (ng/L)
CD	3169.9 ± 219.7	258.8 ± 25.2	130.8 ± 9.2
HFD	3211.3 ± 153.8	265.8 ± 24.2	143.0 ± 15.7
HFD-N	3023.1 ± 180.6	215.2 ± 38.5**	117.9 ± 17.9**
HFD-S	2955.7 ± 257.8*	236.7 ± 21.6*	114.4 ± 19.3**

The contents of CRP, IL-6, and TNF-α in guinea pig plasma were measured by ELISA method after 8 weeks' treatment. Data are presented as mean ± SD (n = 8). *P < 0.05; **P < 0.01 versus HFD group.