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Effect of PTU-induced hypothyroidism and its reversal by T3 upon oxidative damage to mitochondrial proteins. (a) Protein carbonyl content in submitochondrial particles. (b) Protein carbonyl content in mitochondrial matrix fraction isolated from liver of rats. Data are means ± S.D. of five animals/group. Statistical significance is denoted by *P < 0.001 compared to euthyroid rats; ‡ P < 0.005 compared to hypothyroid rats.
