Methods | Randomised observational controlled study. 4 treatment arms: 1 LEV fast rate, 2 LEV slow rate, 3 PGB fast rate, 4 PGB slow rate dosage |
Participants | 128 patients with refractory partial epilepsy (32 in each treatment arm) |
Interventions | Group 1: starting dose of 1000 mg BD LEV fast rate with weekly increments of 500 mg Group 2: starting dose of 500 mg BD LEV slow rate with weekly increments of 250 mg Group 3: starting dose of 300 mg BD PGB fast rate with weekly increments of 150 mg Group 4: starting dose of 150 mg BD PGB slow rate with weekly increments of 75 mg |
Outcomes | Rate of withdrawals and continuation to maximum dose Incidence of adverse events |
Notes | Study reported in abstract form only. Further details of study are unavailable |