Skip to main content
. Author manuscript; available in PMC: 2014 Jun 16.
Published in final edited form as: Cochrane Database Syst Rev. 2008 Jan 23;(1):CD005612. doi: 10.1002/14651858.CD005612.pub2
Methods Randomised observational controlled study. 4 treatment arms: 1 LEV fast rate, 2 LEV slow rate, 3 PGB fast rate, 4 PGB slow rate dosage
Participants 128 patients with refractory partial epilepsy (32 in each treatment arm)
Interventions Group 1: starting dose of 1000 mg BD LEV fast rate with weekly increments of 500 mg
Group 2: starting dose of 500 mg BD LEV slow rate with weekly increments of 250 mg
Group 3: starting dose of 300 mg BD PGB fast rate with weekly increments of 150 mg
Group 4: starting dose of 150 mg BD PGB slow rate with weekly increments of 75 mg
Outcomes Rate of withdrawals and continuation to maximum dose
Incidence of adverse events
Notes Study reported in abstract form only. Further details of study are unavailable