Table 3.
Univariate and multivariate analyses of the pathological complete response in 102 breast cancers
|
Parameter |
|
Univariate analysis |
|
|
Multivariate analysis |
|
|---|---|---|---|---|---|---|
| Odds ratio | 95% CI | p value | Odds ratio | 95% CI | p value | |
| CA9 expression in CNB |
|
|
|
|
|
|
| positive vs negative |
0.24 |
0.09-0.63 |
0.041 |
0.21 |
0.07-0.59 |
0.003 |
| ER |
|
|
|
|
|
|
| positive vs negative |
0.24 |
0.10-0.61 |
0.002 |
0.23 |
0.02-2.37 |
0.219 |
| PgR |
|
|
|
|
|
|
| positive vs negative |
0.22 |
0.08-0.61 |
0.004 |
0.36 |
0.10-1.30 |
0.120 |
| HER2 |
|
|
|
|
|
|
| positive vs negative |
1.75 |
0.68-4.48 |
0.244 |
|
|
|
| Molecular subtypes |
|
|
|
|
|
|
| HR+/HER2- vs others |
0.33 |
0.13-0.83 |
0.018 |
1.78 |
0.18-17.44 |
0.622 |
| HR-/HER2+ vs others |
0.02 |
0.01-2999894 |
0.728 |
|
|
|
| HR-/HER2+ vs others |
1.75 |
0.683-4.483 |
0.244 |
|
|
|
| HR-/HER2- vs others |
1.17 |
0.93-1.46 |
0.176 |
|
|
|
| Age |
|
|
|
|
|
|
| ≥55 vs <55 |
0.88 |
0.37-2.05 |
0.759 |
|
|
|
| Menopause |
|
|
|
|
|
|
| positive vs negative |
0.82 |
0.33-2.05 |
0.677 |
|
|
|
| Tumor size |
|
|
|
|
|
|
| ≥4 cm vs <4 cm |
0.64 |
0.19-2.12 |
0.463 |
|
|
|
| Lymph node status |
|
|
|
|
|
|
| positive vs negative | 4.33 | 0.93-20.1 | 0.061 |