Table 1.
Coronavirus neutralizing antibody titers.
Vaccine (S protein) | Dose (μg) | Adjuvant | Day | GMT | 95% LCL | 95% UCL |
---|---|---|---|---|---|---|
MERS-CoV | 1 | None | 21 | 49 | 17 | 140 |
45 | 320 | 110 | 934 | |||
3 | 21 | 43 | 22 | 85 | ||
45 | 299 | 193 | 461 | |||
10 | 21 | 65 | 33 | 126 | ||
45 | 243 | 104 | 567 | |||
1 | Alum | 21 | 735 | 419 | 1,291 | |
45 | 640 | 251 | 1,630 | |||
3 | 21 | 368 | 171 | 792 | ||
45 | 905 | 505 | 1,624 | |||
1 | Matrix M1 | 21 | 3,378 | 1,804 | 6,325 | |
45 | 1,940 | 1,139 | 3,306 | |||
3 | 21 | 1,194 | 542 | 2,634 | ||
45 | 1,689 | 831 | 3,432 | |||
SARS-CoV | 3 | None | 21 | 86 | 32 | 228 |
45 | 80 | 38 | 168 | |||
Alum | 21 | 970 | 497 | 1,894 | ||
45 | 640 | 330 | 1,240 | |||
Matrix M1 | 21 | 3,152 | 1,624 | 6,117 | ||
45 | 3,152 | 1,864 | 5,329 |
The vaccine groups are shown that were tested for neutralizing antibody titer. Dose, adjuvant type, day of bleeding and geometric mean titer with confidence intervals are shown for each group. N = 10 for each dosing/adjuvant group shown.