Table 2.
Variables (reference) | Univariate
|
Multivariable1
|
||
---|---|---|---|---|
OR (95% CI) | p-Value | OR (95% CI) | p-Value | |
Pretransplant biopsy (No) | 1.25 (1.09–1.43) | 0.001 | 1.07 (0.93–1.24) | 0.330 |
Fulfilling UNOS-DKT criteria (No) | 2.28 (2.07–2.52) | <0.001 | 1.73 (1.54–1.93) | <0.001 |
KDPI %2 (corresponding KDRI-UNOS categories) | ||||
<80% (<1.7) | Referent | – | Referent | – |
≥80% and ≤90% (≥1.7 and ≤2.0) | 1.41 (1.25–1.60) | <0.001 | 1.17 (1.03–1.33) | 0.018 |
>90% (>2.0) | 2.81 (2.50–3.17) | <0.001 | 1.99 (1.74–2.29) | <0.001 |
Transplant center volume 100 kidney transplants/year (<100/year) | 1.06 (0.97–1.18) | 0.192 | 1.03 (0.93–1.15) | 0.553 |
OPTN regions | ||||
Region 1 | Referent | – | Referent | – |
Region 2 | 1.24 (0.96–1.61) | 0.103 | 1.20 (0.92–1.56) | 0.182 |
Region 3 | 0.94 (0.71–1.24) | 0.652 | 1.00 (0.75–1.33) | 0.984 |
Region 4 | 1.06 (0.79–1.42) | 0.645 | 1.16 (0.86–1.57) | 0.329 |
Region 5 | 0.99 (0.75–1.29) | 0.940 | 1.05 (0.79–1.38) | 0.746 |
Region 6 | 0.76 (0.51–1.11) | 0.158 | 0.88 (0.59–1.30) | 0.522 |
Region 7 | 1.28 (0.97–1.69) | 0.076 | 1.29 (0.97–1.71) | 0.078 |
Region 8 | 0.95 (0.68–1.32) | 0.751 | 1.12 (0.80–1.57) | 0.522 |
Region 9 | 1.39 (1.06–1.81) | 0.017 | 1.31 (0.99–1.72) | 0.059 |
Region 10 | 1.22 (0.91–1.63) | 0.168 | 1.36 (1.01–1.83) | 0.041 |
Region 11 | 1.20 (0.91–1.58) | 0.204 | 1.26 (0.95–1.67) | 0.104 |
Mean VIF (variance inflation factor)3 | – | – | 2.30 | – |
DKT, dual kidney transplantation; KDPI, Kidney Donor Profile Index; KDRI, Kidney Donor Risk Index; OPTN, Organ Procurement and Transplantation Network; UNOS, United Network of Organ Sharing.
Total 16 931 observations were included for multivariable analysis.
KDPI is calculated based on a scaling factor of 1.22219212347775, a median KDRI-UNOS value among all deceased kidney donors recovered during 2012.
VIF <10 shows no significant multicolinearity among independent predictors.