Figure 3.

Spermatogonia with apparently normal (A–H) and abnormal (I–L) morphologies in the testes of Utp 14b^jsd mutant mice. Arrowheads indicate nucleoli; arrows indicate vacuoles. Large (I) or numerous (J) nuclear vacuoles are present in nuclei that have diffuse nucleoli and heterochromatin typical differentiated type A sprematogonia. Other abnormalities include large nuclei with increased amounts of hetrochromatin (K) and those with highly reticulated and dispersed nucleoli (L). Bar = 5 µm [30]. Reprinted with permission.