. 2014 Jun 16;5:282. doi: 10.3389/fimmu.2014.00282

Table 1.

Emerging subsets of ILC1 and tissue-resident NKs.

	CD127	IL-15 dependence	IL-7 dependence	TBX21 dependence	Eomes dependence	E4BP4 dependence	Human counterpart
siLP ILC1	+++	Yes	No	Yes	No	Partial	Most likely CD127⁺CD56⁻CD94⁻mucosal cells
Intraepithelial ILC1	−	Partial	No	Yes	TBD	Yes	CD56⁺NKp44⁺
							CD103⁺CD160⁺ cells in human tonsil and intestine
“Converted” or “plastic” ILC3	+++	No, but IL-15 can promote conversion	Yes	Yes	No	TBD	Mostly generated in vitro
cNKs (splenic, bone marrow, lymph nodes)	−	Yes	No	Yes	Yes	Yes	Most likely CD56im^dimCD16⁺ blood NKs
Thymic NK cells	+++	Yes	Yes	Yes	Yes	Yes	Most likely CD56right^brightCD16⁻blood NKs
Liver-resident CD49a⁺DX5⁻NKs/ILC1	−	Yes	TBD	Yes	No	No	TBD
Skin-resident CD49a⁺DX5⁻NKs	−	Yes	TBD	Yes	TBD	No	TBD
Uterus-resident CD49a⁺DX5⁻NKs	−	Yes	TBD	No	TBD	No	TBD
Salivary gland NKs	−	Yes	TBD	TBD	TBD	No	TBD

TBD, to be determined.