Table 6.
Comparison of initial and final versions of the pediatric severe sepsis screening tool.
| Measure | Original ICCPS (2) based tool | Final revised tool |
|---|---|---|
| Total cases/gold standard severe sepsis (GSSS) cases | 7,402/38 | 7,402/38 |
| SIRS firingsa/percentage of total cases | 1,772/23.9 | 315/4.3 |
| False positives/false negatives | 217/1 | 39/1 |
| Sensitivity/specificity (%) | 97.4/97.1 | 97.4/99.5 |
| Positive predictive/negative predictive value (%) | 14.6/99.99 | 48.7/99.99 |
| Area under the curve (AUC) | 0.972 | 0.984 |
| Median time from arrival to tool firing for GSSS cases | 10.3 h (P25 = 2.8, P75 = 20.6) | 11.1 h (P25 = 5.0, P75 = 22.2) |
aSIRS Firing indicates that the tool “detected” the presence of SIRS based on the criteria used by the tool.