Fig. 4.
Drug released from cyclodextrin:HDI polymers sterilized by autoclave compared to non-sterilized that were loaded with (A, B) erythromycin, (C, D) vancomycin, and (E, F) rifampicin after sterilization. (Left) The percentage of drug released slowed significantly after autoclaving (p<0.05), and (Right) the total amount of drug released was significantly lower in autoclaved polymers compared to non-sterilized controls (p<0.0001). Each drug releases at a different rate and therefore is presented on a different time scale.