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. Author manuscript; available in PMC: 2015 May 14.
Published in final edited form as: J Mater Chem B. 2014 May 14;2(18):2764–2772. doi: 10.1039/C4TB00083H

Fig. 6.

Fig. 6

Zone of inhibition (Kirby-Bauer) assay from cyclodextrin:HDI polymers sterilized by autoclave, ethylene oxide, and gamma radiation compared to non-sterilized polymers that were loaded with (A, B) erythromycin, (C, D) vancomycin, and (E, F) rifampicin after sterilization. (A) The bactericidal activity of autoclaved gels with erythromycin is significantly smaller for the first five days (p<0.05) yet significantly larger after 11 days (p<0.05). (C) The bactericidal activity of autoclaved gels with vancomycin is significantly smaller for the first 10 days (p<0.05) yet significantly larger after 16 days (p<0.05). (E) Bactericidal activity of rifampicin loaded autoclave sterilized disks was similar to that of non-sterilized disks for over 8 months (243 days). (B, D, F)Bactericidal activity from ethylene oxide or gamma radiation sterilized, drug-loaded polymers showed no difference from the activity from non-sterilized polymers loaded with erythromycin, vancomycin, or rifampicin.