Table 1.
Comparison of the different methods for analyzing heart function in Drosophila.
| Method | Effect on Animal |
Heart Rate |
Systolic & Diastolic Intervals |
Systolic & Diastolic Diameters |
Rhythmicity | Structure | Stiffness | Stress Response |
|---|---|---|---|---|---|---|---|---|
| Gross Δ Intensity Optical Method | Stressful / in vivo | + | + | |||||
| SOHA Optical Method | Invasive / in situ | + | + | +/− 1µ | + | + | ||
| Atomic Force Microscopy | Invasive / in situ | + | ||||||
| Optical Coherence Tomography | Stressful / in vivo | + | +/− 10µ | + | + | |||
| Electrical Recordings | Invasive / in situ | + | + | + | ||||
| Immuno histochemistry / Electron Microscopy | in situ | ++ | ||||||
| Electrical Pacing | Stressful / in vivo | + |