Table 1.

Characteristics of pediatric cancer cases ages 0–18 in Utah

	All pediatric cases		Cases with family history available		Cases without family history available
	N (%)		N (%)		N (%)		p 1
Total	6,338	100.0	4,482	70.7	1,856	29.3
Place of birth
In Utah	3,724	58.8	3,673	82.0	51	2.7
Outside of Utah	2,614	41.2	809	18.0	1,805	97.3	<0.0001
Gender
Female	2,962	46.7	2,130	47.5	832	44.8
Male	3,376	53.3	2,352	52.5	1,024	55.2
Year of diagnosis
1966–1979	1,332	21.0	930	20.7	402	21.7
1980–1989	1,407	22.2	973	21.7	434	23.4
1990–1999	1,697	26.8	1,225	27.3	472	25.4
2000–2009	1,902	30.0	1,354	30.2	548	29.5
Age at diagnosis
0–4	2,247	35.5	1,552	34.6	695	37.4
5–18	4,091	64.5	2,930	65.4	1,161	62.6
Last follow-up year in Utah
No Utah follow-up	1,530	24.1	104	2.3	1,426	76.8
Same as birth year	94	1.5	87	1.9	7	0.4
1–4 years > birth year	517	8.2	439	9.8	78	4.2
5+ years > birth year	4,197	66.2	3,852	85.9	345	18.6	<0.0001
Vital status
Alive at last follow-up	4,307	68.0	3,020	67.4	1,287	69.3
Deceased, cancer	1,185	18.7	1,052	23.5	133	7.2
Deceased, other/unknown	846	13.3	410	9.1	436	23.5	<0.0001
Multiple primary cancers
First primary only	6,167	97.3	4,340	96.8	1,827	98.4
Multiple primaries	171	2.7	142	3.2	29	1.6	<0.001
Total pediatric tumors (ICCC-3)	6,399	100.0	4,528	71.4	1,871	29.5
Leukemias, myeloproliferative, myelodisplastic diseases	1,686	26.3	1,150	25.4	536	28.6	<0.01
CNS, misc. intracranial and intraspinal neoplasms	1,270	19.8	870	19.2	400	21.4
Lymphomas, reticuloendothelial neoplasms	795	12.4	578	12.8	217	11.6
Other malignant epithelial neoplasms, malignant melanomas	584	9.1	480	10.6	104	5.6	<0.0001
Soft tissue and other extraosseous sarcomas	425	6.6	304	6.7	121	6.5
Malignant bone tumors	403	6.3	258	5.7	145	7.7	<0.01
Neuroblastoma, other peripheral nervous cell tumors	377	5.9	254	5.6	123	6.6
Germ cell tumors, trophoblastic tumors, neoplasms of gonads	337	5.3	262	5.8	75	4.0	<0.01
Renal tumors	291	4.5	203	4.5	88	4.7
Retinoblastomas	125	2.0	87	1.9	38	2.0
Hepatic tumors	77	1.2	60	1.3	17	0.9
Not classified or in situ	29	0.5	22	0.5	7	0.4

¹Chi-squared test of association between cases with and without genealogy; p-values > 0.01 are not displayed.

Abbreviations: ICCC-3: International Classification of Childhood Cancer, Third edition¹³; CNS: central nervous system.