2. Effectiveness data from open label trials.

		1year n/N (%)	2year n/N (%)	3year n/N (%)	4year n/N (%)	5year n/N (%)
Schumacher 2009	Febuxostat 40 mg	4/7  (57)	5/8   (63)	4/ 6 (67)	5/ 6 (83)	6/6 (100)
	Febuxostat 80 mg	47/55 (85)	37/49      (76)	38/ 45 (84)	36/39 (92)	38/41 (93)
	Febuxostat 120 mg	12/18      (67)	12/13      (92)	12/13 (92)	11/13 (85)	10/11 (91)
Becker 2009	Febuxostat 80 mg	375/422  (89)	325/364  (89)	109/120  (91)	‐	‐
	Febuxostat 120 mg	145/168  (86)	123/141  (87)	43/47      (92)	‐	‐
	Allopurinol 300 mg	37/45      (82)	33/42      (79)	9/10        (90)	‐	‐

Proportion of subjects with serum uric acid < 6 mg/dL