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. Author manuscript; available in PMC: 2014 Jun 16.
Published in final edited form as: Cochrane Database Syst Rev. 2012 Apr 18;4:CD009148. doi: 10.1002/14651858.CD009148.pub2
Methods Randomised.
Participants 2289 women referred for Dopplers studies and for antenatal fetal monitoring
Interventions Continuous wave Doppler studies of umbilical artery.
Outcomes “Fetal outcome: perinatal mortality, Apgar score and admission to the neonatal unit. Obstetric intervention: admission to hospital, induction of labour and caesarean section. Use of tests of fetal well being: cardiotocography, biophysical profile and ultrasound biometry.”
Notes
Risk of bias
Bias Authors’ judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not described.
Allocation concealment (selection bias) Unclear risk Not described.
Blinding of participants and personnel (performance bias)
All outcomes
High risk Not blinded.
Blinding of outcome assessment (detection bias)
All outcomes
High risk Not blinded.
Incomplete outcome data (attrition bias)
All outcomes
Low risk Data appears to have been analysed according to the intention-to-treat principle. It states that 24 women randomised to Doppler didn’t have it carried out and 3 randomised to no Doppler, actually had Dopoler. Data on outcomes in table 3 suggest analysis was based on randomised groups
Loss to follow-up - one patient appears to be missing from non Doppler group - table 4 - so minimal loss
Selective reporting (reporting bias) Low risk All outcomes specified within the abstract are reported upon in the paper
Other bias Low risk Baseline characteristics similar. “The treatment and control groups were comparable in age, parity, gestation at point of entry and risk features.”