Methods	Randomised.
Participants	735 women with high-risk pregnancies referred for fetal well-being testing
Interventions	Fetal biophysical profile versus non-stress test.
Outcomes	Apgar score, positive and negative predictive value of the test
Notes
Risk of bias
Bias	Authors’ judgement	Support for judgement
Random sequence generation (selection bias)	Low risk	Randomly assigned -using flip of a coin.
Allocation concealment (selection bias)	Unclear risk	Not described.
Blinding of participants and personnel (performance bias) All outcomes	Low risk	“Neither patient nor referring physician was aware of which testing scheme had been assigned.” Study also described as “prospective blind study” - blinding only broken in women in whom a major lethal fetal anomaly was detected
Blinding of outcome assessment (detection bias) All outcomes	High risk	Not blinded.
Incomplete outcome data (attrition bias) All outcomes	Low risk	All patients appear to be accounted for within the results tables: scheme A, N=360 scheme B, N=375, total number patients referred = 735
Selective reporting (reporting bias)	Unclear risk	Unclear - not clearly documented which outcomes were to be collected as part of the study
Other bias	Low risk	“Obstetric risk factors at initial referral did not vary significantly between groups.”