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. Author manuscript; available in PMC: 2015 Jan 1.
Published in final edited form as: Cancer Prev Res (Phila). 2013 Nov 26;7(1):169–178. doi: 10.1158/1940-6207.CAPR-13-0299

Figure 4.

Figure 4

eRapa does not reduce mediators of T. gondii immunity during active infection. BL6 mice were infected with 10,000 Me49 strain T. gondii tachyzoites expressing an OVA reporter antigen by intraperitoneal challenge and mice were sacrificed 11 days later. Immune events were acquired from single-cell spleen suspensions on a Becton-Dickinson LSRII. Individual symbols represent individual mice and the bar is the median value. CD69 is an activation marker. Foxp3 is a regulatory T cell marker. CD44+CD62L− cells are memory T cells. CD44−CD62L+ cells are naive T cells. CTRL, mice fed Eudragit control chow. RAPA, mice fed chow with rapamycin 14 ppm. IFNγ, interferon-γ. “Antigen specific” refers to CD8+ T cells recognizing the SIINFEKL sequence of the OVA antigen engineered into T. gondii tachyzoites. No differences were statistically significant.