Skip to main content
. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: Biomaterials. 2014 Feb 3;35(12):3744–3755. doi: 10.1016/j.biomaterials.2013.12.078

Figure 1.

Figure 1

Patterned, RGD-modified silk films induce cell alignment. A scanning electron micrograph shows the patterned silk film substratum (a). Confocal laser-scanning micrographs of hCSSCs grown on patterned silk films without (b, e) and with (c, f) RGD surface modification. hCFs (d, g) grown on patterned silk films with RGD surface modification. hCF cells plated on surfaces without RGD modification did not adhere (not shown). Day 1 of culture (b, c, d) and day 3 (e, f, g). Cells were labeled using fluorescent viability marker dye Calcein AM. Arrows indicate direction of grooves in the silk substratum.