Table 2.
Bivariate comparisons of PsA and RA patients, last visit*
| All PsA |
All RA |
PsA, without malignancy |
PSA, with malignancy |
P- value |
RA, without malignancy |
RA, with malignancy |
P- value |
|
|---|---|---|---|---|---|---|---|---|
| N=2970 | N=19260 | N=2930 | N=40 | N=18953 | N=307 | |||
| Age, years | 53.6 (12.6) | 60.2 (13.6) | 53.5 (12.6) | 62.5 (11.7) | <0.001 | 60.1 (13.7) | 66.1 (11.4) | <0.001 |
| Female | 1525 (51.6) | 14709 (76.7) | 1506 (51.7) | 19 (47.5) | 0.598 | 14490 (76.8) | 219 (71.6) | 0.033 |
| Caucasian | 2700 (91.6) | 15905 (83.5) | 2661 (91.6) | 39 (97.5) | 0.178 | 15632 (83.4) | 273 (89.8) | 0.003 |
| Current smoker | 433 (14.6) | 3136 (16.4) | 429 (14.7) | 4 (10.0) | 0.404 | 3098 (16.4) | 38 (12.4) | 0.058 |
| Past smoker | 866 (29.3) | 6156 (32.1) | 846 (29.0) | 20 (50.0) | 0.004 | 6026 (31.9) | 130 (42.3) | <0.001 |
| Alcohol use | 1672 (58.6) | 8321 (44.9) | 1653 (58.8) | 19 (48.7) | 0.206 | 8196 (45.0) | 125 (43.1) | 0.526 |
| BMI, kg/m2 | 31.2 (7.4) | 29.1 (7.2) | 31.2 (7.5) | 31.4 (6.2) | 0.859 | 29.1 (7.2) | 28.2 (6.6) | 0.022 |
| Disease duration, years | 10.8 (9.0) | 12.1 (10.1) | 10.7 (9.0) | 13.5 (10.9) | 0.053 | 12.0 (10.1) | 14.2 (10.0) | <0.001 |
| CRP, mg/L | 1.6 (4.1) | 2.3 (6.5) | 1.6 (4.1) | 1.4 (2.2) | 0.913 | 2.3 (6.5) | 3.5 (9.5) | 0.050 |
| CDAI, (0–76) | 8.1 (9.2) | 10.3 (10.9) | 8.1 (9.2) | 8.7 (9.0) | 0.674 | 10.3 (10.9) | 9.6 (10.0) | 0.219 |
| DMARD history | 2857 (96.2) | 18982 (98.6) | 2817 (96.1) | 40 (100.0) | 0.206 | 18676 (98.5) | 306 (99.7) | 0.098 |
| MTX history | 2278 (76.7) | 16803 (87.2) | 2242 (76.5) | 36 (90.0) | 0.045 | 16524 (87.2) | 279 (90.9) | 0.054 |
| anti-TNF history | 2088 (70.3) | 11388 (59.1) | 2060 (70.3) | 28 (70.0) | 0.966 | 11209 (59.1) | 179 (58.3) | 0.768 |
| Other biologic history | 70 (2.4) | 2379 (12.4) | 70 (2.4) | 0 (−0.0) | 0.323 | 2349 (12.4) | 30 (9.8) | 0.166 |
| Current DMARD | 2553 (86.0) | 17100 (88.8) | 2522 (86.1) | 31 (77.5) | 0.121 | 16850 (88.9) | 250 (81.4) | <0.001 |
| Current MTX | 1336 (45.0) | 11445 (59.4) | 1320 (45.1) | 16 (40.0) | 0.524 | 11272 (59.5) | 173 (56.4) | 0.269 |
| Current anti-TNF | 1712 (57.6) | 7301 (37.9) | 1695 (57.8) | 17 (42.5) | 0.051 | 7213 (38.1) | 88 (28.7) | <0.001 |
| Current other biologic | 23 (0.8) | 1530 (7.9) | 22 (0.8) | 1 (2.5) | 0.210 | 1516 (8.0) | 14 (4.6) | 0.027 |
| Family history of cancer | 1290 (43.4) | 9019 (46.8) | 1275 (43.5) | 15 (37.5) | 0.446 | 8863 (46.8) | 156 (50.8) | 0.158 |
*
Dichotomous variables are expressed as number (%); continuous variables are expressed as mean (SD)