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. Author manuscript; available in PMC: 2015 May 23.

Published in final edited form as: Circ Res. 2014 May 23;114(11):1757–1771. doi: 10.1161/CIRCRESAHA.114.301174

Table 2.

Vascular mononuclear phagocytes in pre-lesional arteries.

Species	Phenotype	Comments	References
Human	CD1a+ Langerin+ S-100+ CD68-CD83-CD86-, also lacking von Willebrand factor and smooth muscle actin	Specimen of various human arteries; positive for DC markers with no hint of macrophage character since cells were CD68-. Only single stains were carried out, so co-expression of the markers has not been established. MHC II was not stained.	^{7, 140}
Rabbit	MHC II+	Morphology of arterial MPs consistent with DCs or macrophages. Distribution of cells also similar to mouse artery MP.	⁷
Mouse	CD68+ MHC II+ CD11c+ 33D1+ CD11b^low; mRNA for CD14 and CD83; GFP+ in CX3CR1^gfp/- mouse	33D1 is a DC marker not described on macrophages. CD11b can be absent from macrophages or DCs, but is always present on monocytes. Difficult to fully reconcile with flow cytometry evaluation	^{6, 8, 10, 24}