Table 3.
Conventional and novel roles of apolipoprotein E.
Function | Relevant Organ or Cells Expressing apoE | References |
---|---|---|
VLDL clearance from plasma | liver | Reviewed in 52 |
Maintains homeostasis of HDL | liver | Reviewed in 52, 141 |
Regulates cholesterol distribution in signaling domains of proliferating hematopoietic stem cells | Myeloid stem cells | 49 |
Macrophage phenotypic polarization? | macrophages | 55 |