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. 2014 Apr 11;289(24):16802–16813. doi: 10.1074/jbc.M113.545236

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© 2014 by The American Society for Biochemistry and Molecular Biology, Inc.

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FIGURE 3. — Membrane properties of Kcne3^+/+versus Kcne3^−/− SGNs at P12, the genesis of hearing. A, assessment of the evoked P12 SGN APs from rapidly adapting neurons isolated from the apical aspects of the cochlea from the Kcne3^+/+ (left panel) and Kcne3^−/− mice (middle panel) and superimposed traces (right panel). The recording conditions were identical in the wild-type and null mutant neurons. APs were evoked by injecting 0.1 nA current for ∼250 ms. B, representative recordings from slowly adapting SGNs from the base of the cochlea showing APs from Kcne3^+/+(left panel) and Kcne3^−/− (middle panel) neurons. We superimposed traces (right panel) for comparison. C–F, summary data from analyses of AP properties. C, threshold voltage; D, extent of AHP; E, AP amplitude, and F, AP duration. Significant differences are noted, where *, p < 0.05; **, p < 0.01. Also see Table 1 where the number of samples is listed.