FIGURE 1.

LPS induces Nrf2 protein accumulation. A and B, BMMs generated from naïve C57BL/6 mice were stimulated with LPS (400 ng/ml) for the indicated periods. Protein (A) and transcript (B) of Nrf2 was measured by immunoblotting and RT-PCR, respectively. C, BMMs generated from WT or Myd88^−/− mice were stimulated with LPS (400 ng/ml) for the indicated periods. Immunoblotting was performed to measure the protein levels of indicated molecules. Values in B are expressed as the mean ± S.D., and the results are representative of three independent experiments.