TABLE 1.

SPR derived binding kinetics

^a The kinetic rate constants were obtained using a simple first-order. (1:1) Langmuir bimolecular interaction model. The kinetic values represent the average of triplicates.

^b The steady-state affinity constants were obtained using an equilibrium (R_eq) binding model supplied by the BIAevaluation software (version 4.1). The affinities derived from equilibrium binding data represent the average of triplicates.

^c NA, not acquired because of fast binding kinetics.