Table 3.4.
Distribution of Kiss1r mRNA based on RT-PCR, in situ hybridization using radioactive probes (ISH) or immunohistochemistry for β-galactosidase (β-gal)
| Species | MBH /ARC* |
Preoptic region POA/RP3V |
AHA | DMH | PH | LHA | Medial Septum |
Hippo /DG |
Medial Amgdala |
Locus Coer. |
GnRH neurons |
Other Regions |
eReferences | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Human (PCR) | ++ | +++ | +++ | ++ | +a | 76,77 | ||||||||
| Rhesus Monkey (PCR) | + (M) ++(F) | ++(M) +(F) | 43,80,81 | |||||||||||
| Mouse (PCR) | ++ | ++ | ++ | +++ | + | 95% | +b | 86 | ||||||
| Mouse (β-gal) | − | ++ | − | − | − | ++ | − | ++ | +++ | − | + | 40–70% | +c | 79,90 |
| Rat (PCR) | + | ++ | ++ | + | 22,82–85 | |||||||||
| Rat (ISH) | +++ | ++ | ++ | +++ | ++ | +++ | P | +++ | +++ | +++ | 77% | +d | 20,78 | |
| Sheep (ISH) | P | P | + | 78–90% | 87 – 89 | |||||||||
*
PCR data is from MBH in humans and ARC in rodents and sheep
P: present but not quantified (from reports of Kiss1r in GnRH neurons)
a
Other regions include: Thalamus, substantial nigra, cingulated gyms;
b
Other regions include: cerebellum, striatum;.
c
Other regions include: supramammillary nucleus, anteroventralthalamus, hibenula; periaqueductal gray;
d
Other regions include: zona incerta, olfactory cortex, ventral premammillary, periaqueductal gray
e
Reference numbers are from citations at end of chapter