Table 4. Shifts in site frequency spectra for each amino acid, Monte Carlo analyses^a.

Amino Acid	P-Value,b All Sites, Parsimony	P-Value, All Sites, Bayesian	P-Value, No Singletons, Parsimony	P-Value, No Singletons, Bayesian
ala	0c	0	0	0
arg	0	0	0.02667	0.01952
asn	0	0	0.00238	0.00542
asp	0	0	0.00001	0.00002
cys	0.00002	0.00008	0.00273	0.00527
gln	0	0	0	0
glu	0	0	0	0
gly	0	0	0.02055	0.01272
his	0	0	0.00337	0.00969
ile	0	0	0.00001	0.00002
leu	0	0	0	0
lys	0	0	0	0
phe	0	0	0	0
pro	0	0	0.00009	0.00008
ser	0	0	0	0
thr	0	0	0	0.00001
tyr	0	0	0.00007	0.00067
val	0	0	0	0

^aPermutation test of Llopart et al. (2008).

^bAll P-values are for 1-tailed tests.

^cA reported estimate of 0 indicates that none of 100,000 data permutations led to a higher value of the test statistic.