Figure 1.
Abridged yeast phospholipid biosynthetic de novo and Kennedy pathways. Genes encoding biosynthetic enzymes are italicized and boxed. Those genes noted in green and orange are nonessential and essential (respectively) and yield an Opi− phenotype when mutated. PA, phosphatidic acid; CDP-DAG, CDP-diacylglycerol; PI, phosphatidylinositol; PC, phosphatidylcholine; and C, choline