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. 2014 May 21;57(11):4950–4961. doi: 10.1021/jm5004842

Table 2. Compound 2 Other Linkers.

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a

cLogD calculated at pH 7.4 by ACD Labs Percepta.

b

pKa calculated by ACD Labs Percepta.

c

RPA IC50 represents mean ± SEM (μM); assays represent duplicate independent biological experiments.

d

NCL IC50 represents mean ± SEM (μM); assays represent duplicate independent biological experiments.