Table 2.
Weighted mean effect sizes and homogeneity statistics by follow-up interval*
| d+ (95% CI) | d+ (95% CI) | Homogeneity of effect sizes | |||||
|---|---|---|---|---|---|---|---|
|
|
|||||||
| Outcome | k | Fixed effects | k | Random effects | Q | P | I2 (95% CI) |
| Early Assessments (<52 weeks) | |||||||
| Abstinence/delay of sex | 6 | 0.07 (0.02, 0.12) | 6 | 0.15 (−0.05, 0.36) | 82.47 | <.001 | 94% (89, 97) |
| Condom use‡ | 7 | 0.17 (0.11, 0.23) | 7 | 0.23 (0.03, 0.44) | 56.14 | <.001 | 89% (80, 94) |
| Multiple partners | 3 | 0.95 (0.83, 1.07) | 3 | 0.31 (−0.75, 1.36) | 67.38 | <.001 | 97% (94, 98) |
| Late Assessments (≥ 52 weeks) | |||||||
| Abstinence/delay of sex | 6 | 0.15 (0.11, 0.20) | 6 | 0.19 (0.05, 0.33) | 43.79 | <.001 | 89% (78, 94) |
| Condom use‡ | 6 | 0.19 (0.13, 0.25) | 6 | 0.18 (0.01, 0.36) | 36.16 | <.001 | 86% (72, 93) |
| Multiple partners | 3 | 0.44 (0.35, 0.53) | 3 | 0.18 (−0.77, 1.14) | 181.15 | <.001 | 99% (98, 99) |
| Alcohol use | 2 | 0.06 (−0.03, 0.15) | 2 | −0.03 (−0.37, 0.30) | 9.28 | .002 | 89% (60, 97) |
| Drug use | 3 | 0.05 (−0.02, 0.12) | 3 | 0.04 (−0.16, 0.24) | 14.13 | .001 | 86% (59, 95) |
| HSV-2 | 2 | 0.17 (0.09, 0.25) | 2 | 0.17 (0.07, 0.26) | 1.31 | .253 | 23% (0, 67) |
| HIV | 2 | −0.10 (−0.19, 0.02) | 2 | −0.10 (−0.24, 0.03) | 2.56 | .110 | 61% (0, 93) |
| Last Assessment† | |||||||
| Abstinence/delay of sex | 10 | 0.04 (0.01, 0.08) | 10 | 0.12 (−0.01, 0.24) | 121.18 | <.001 | 93% (88, 95) |
| Condom use‡ | 10 | 0.13 (0.09, 0.18) | 10 | 0.17 (0.04, 0.29) | 60.68 | <.001 | 85% (74, 91) |
| Multiple partners | 4 | 0.43 (0.34, 0.53) | 4 | 0.09 (−0.75, 0.93) | 183.95 | <.001 | 98% (97, 99) |
| Alcohol use | 2 | 0.06 (−0.03, 0.15) | 2 | −0.03 (−0.37, 0.30) | 9.28 | .002 | 89% (60, 97) |
| Drug use | 3 | 0.03 (−0.04, 0.10) | 3 | 0.04 (−0.36, 0.44) | 51.90 | .001 | 96% (92, 98) |
| HSV-2 | 2 | 0.17 (0.09, 0.25) | 2 | 0.17 (0.07, 0.26) | 1.31 | .253 | 23% (0, 67) |
| HIV | 2 | −0.10 (−0.19, 0.02) | 2 | −0.10 (−0.24, 0.03) | 2.56 | .110 | 61% (0, 93) |
*
Weighted mean effect sizes, d+, for which the 95% confidence interval does not include a zero are significant. Effect sizes are based on fixed- and random-effects assumptions. k, number of interventions. Boldface text highlights significant values.
†
On average, the last assessment occurred 65 weeks post-intervention and ranged from 0 to 104 weeks (median = 78 weeks).