. 2008 Nov;295(5):G987–G995. doi: 10.1152/ajpgi.90272.2008

Table 1.

Contribution of trans fats and high-fructose corn syrup to morphological, biochemical, and histological abnormalities of the ALIOS model at 16 wk

	Control	ALIOS	ALIOS Minus Trans Fats	ALIOS Minus HFCS
Weight, g	27.7±2.9^a	39.2±2.5^b	37.3±2.6^b,c	35.6±3.4^c
Liver weight, g	0.91±0.08^a	1.67±0.23^b	1.19±0.09^c	1.41±0.29^d
Liver triglyceride, mg/g	43±9^a	123±72^b	69±25^a,b	100±53^b
ALT, U/l	31±6^a	83±34^b	41±15^a	83±32^b
Plasma cholesterol, mg/dl	80±6^a	143±12^b	136±19^b	138±21^b
Plasma triglycerides	59±8^a	70±12^a	106±14^b	66±17^a
GTT AUC		2,098±632^a	1,876±234^a	1,709±461^a
GTT glucose at 80 min, mM		15.2±4.1^a	14.9±3.6^a	11.2±1.8^b

Variance statistic is SD. Glucose tolerance testing (GTT) was not performed on control mice at the same time as the other 3 treatment groups. ALIOS, American Lifestyle-Induced Obesity Syndrome; HFCS, high-fructose corn syrup; ALT, alanine aminotransferase; AUC, area under the curve. Superscript letters denote significant differences among the treatment groups (i.e., there is no difference among values annotated with the same letter), P < 0.05 by ANOVA.